• A+
• A+
• A+

Adjust font size

GuideWisdom™

This WisdomCard managed by: Chris Miller

Thyroxine-binding globulin (TBG) binds Thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. ...read more at Wikipedia

Fast Facts:

• -- TBG's are normally higher when tested on newborns.¹
• -- Most of the TGB is attached to both T3 and T2 with less than 1% being unattached.²
• -- Drugs that may increase TBG test results: estrogen, heroin, methadone and phenothiazines.¹
• -- Drugs that may decrease TBG test results: depakote, phenytoin, male hormones and prednisone.¹

Top Resources on Thyroxine-Binding Globulin

• Wikipedia: Thyroxine-Binding Globulin
• eMedicine: Thyroxine-Binding Globulin Deficiency
• A.D.A.M. (via MedlinePlus): Serum TBG Level
• Laboratory Corporation Of America: Thyroxine-Binding Globulin (TBG) - Serum
• Healthwise (via Yahoo Health): Thyroid Hormone Tests
• Merck Manual: Thyroid Gland Disorder - Introduction

Related WisdomCards

• Hypothyroidism
• Hyperthyroidism
• Weight Gain
• Weight Loss
• Fatigue
• Thyroid Scan
• Thyroid Disease
• Goiter

GuideWisdom and Fast Facts References

1. ↑ ^{1.0 1.1 1.2} A.D.A.M. (via MedlinePlus): Serum TBG Level
2. ↑ Healthwise (via Yahoo Health): Thyroid Hormone Tests

User Recommended Links for Thyroxine-Binding Globulin

Are we missing any great links? Please Login or Register to be the first to add to this list of recommended links to help others and improve this WisdomCard.