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Statins

This WisdomCard managed by: Chris Miller

The statins (or HMG-CoA reductase inhibitors) form a class of hypolipidemic drugs used to lower cholesterol levels in people with or at risk of cardiovascular disease. They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver stimulates LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream and a decrease in blood cholesterol levels....read more from Wikipedia

Fast Facts:

  • --Statins lower LDL cholesterol (so-called "bad cholesterol") by 30–50%.
  • --Serious side effects are uncommon. Although rare, liver toxicity can occur.
  • --Studies have linked statins to decreased risks of diabetes and dementia.

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