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GuideWisdom™

This WisdomCard managed by: Nicole Kinsey

Variations in the DNA sequences of humans -- called single nucleotide polymorphism (SNPs) -- can affect how an individual develops diseases and responds to pathogens, chemicals, drugs, vaccines, and other agents. SNP rs7903146 has been strongly associated with type 2 diabetes, as well as an increased risk of colon cancer.

Top Resources on Rs7903146

• SNPedia: rs7903146
• Diabetes Journal: Polymorphisms in the Transcription Factor 7-Like 2 (TCF7L2) Gene Are Associated With Type 2 Diabetes in the Amish
• BMC Medical Genetics: TCF7L2 rs7903146 Variant Does Not Associate With Smallness For Gestational Age in the French Population
• Cancer Epidemiology Biomarkers & Prevention: Transcription Factor 7–like 2 Polymorphism and Colon Cancer
• New Research Findings: The Consistent Association Between rs7903146 in TCFL2 and Type 2 Diabetes
• FreshPatents: Genetic Variants in The tcf7l2 Gene as Diagnostic Markers for Risk of Type 2 Diabetes Mellitus
• PubMed: rs7903146 Articles
• Whitehead Institute for Biomedical Research: Deciphering the Human Genome and the MS Project

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