Methotrexate WisdomCard

Our Guides and Physician Review team have organized the Top 10 Health Resources on Methotrexate and compiled helpful research notes below.


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Research Notes on Methotrexate

Methotrexate is an antimetabolite and antifolate drug that inhibits the metabolism of folic acid. Methotrexate works by slowing the growth of cells, making it an effective drug to treat cancer, psoriasis, rheumatoid arthritis and ectopic pregnancy. Methotrexate is sold under the brand names Rheumatrex, Trexall, Amethopterin, and MTX.

Fast Facts:

  • Can be administered through oral tablet or injection.
  • Serious, sometimes fatal, side effects can occur.
  • Methotrexate taken with penicillin can cause a severe reaction.

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