Macrocephaly WisdomCard

Our Guides and Physician Review team have organized the Top 10 Health Resources on Macrocephaly and compiled helpful research notes below.


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Research Notes on Macrocephaly


Macrocephaly occurs when the head of a person is abnormally large; this includes the scalp, the cranial bone, and the contents of the cranium.1 Macrocephaly refers to a head circumference greater than two standard deviations above the mean for age, sex, race and gestation. Since macrocephaly is a statistical concept, a percentage of children with large heads will be normal.2

Fast Facts:

  • Macrocephaly may be due to megalencephaly (enlarged brain), to hydrocephalus (water on the brain), cranial hyperostosis (bone overgrowth), and other conditions.3
  • An increased head circumference can increase the intracranial pressure.4
  • Every child with macrocephaly or microcephaly or an increasing or decreasing rate of head growth should be evaluated.2

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Research Notes References

  1. Wikipedia: Macrocephaly
  2. 2.0 2.1 Children's Healthcare of Atlanta: Macrocephaly
  3. Wikipedia: Macrocephaly Causes
  4. A.D.A.M. (via Medline Plus): Increased Head Circumference

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