Hypohidrotic Ectodermal Dysplasia WisdomCard

Our Guides and Physician Review team have organized the Top 10 Health Resources on Hypohidrotic Ectodermal Dysplasia and compiled helpful research notes below.


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Research Notes on Hypohidrotic Ectodermal Dysplasia


Hypohidrotic ectodermal dysplasia is one of about 150 types of ectodermal dysplasia in humans. Before birth, these disorders result in the abnormal development of structures including the skin, hair, nails, teeth, and sweat glands. It is associated with distinctive facial features including a prominent forehead, thick lips, and a flattened bridge of the nose. Additional features of this condition include thin, wrinkled, and dark-colored skin around the eyes; chronic skin problems such as eczema; and a bad-smelling discharge from the nose (ozena). ...read more from Wikipedia

Fast Facts:

  • This condition is the most common form of ectodermal dysplasia in humans.1
  • It is caused by an abnormality in the EDA, EDAR, and EDARADD genes, which provide instructions for making proteins that work together during embryonic development.1
  • Some of the symptoms include absence or malformation of certain teeth, sparse hair, and reduced sweating.2
  • It affects at least 1 in 17,000 people worldwide.3

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Research Notes References

  1. 1.0 1.1 Wikipedia: Hypohidrotic Ectodermal Dysplasia
  2. National Organization for Rare Disorders (NORD): Hypohidrotic Ectodermal Dysplasia
  3. Genetic Home Reference: Hypohidrotic Ectodermal Dysplasia

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