Hyaluronic Acid WisdomCard

Our Guides and Physician Review team have organized the Top 10 Health Resources on Hyaluronic Acid and compiled helpful research notes below.


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Research Notes on Hyaluronic Acid


Hyaluronic acid -- also called HA, hyaluronan or hyaluronate -- is a substance found in the connective tissue of the body that cushions and lubricates. Hyaluronic acid is used for osteoarthritis, skin treatments, as a filler for scars and wrinkles, as a lip plumper, as a tumor marker for some cancers, and during and after cataract surgery.1 Injection of hyaluronic acid into arthritic joints is called viscosupplementation.2

Fast Facts:

  • Brand names for HA viscosupplementation include Hyalgan, Synvisc, Artzal, and Nuflexxa.2
  • HA injections tend to give more relief for osteoarthritis than oral medications, but may not work for everyone.3
  • HA for injection into deeper wrinkles on the face include the brand names Restylane and Juvederm.4

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Research Notes References

  1. Wikipedia: Hyaluronan
  2. 2.0 2.1 MyOsteoarthritisCentral: Hyaluronic Acid Injections (Viscosupplementation)
  3. FamilyDoctor: What are Hyaluronic Acid Injections?
  4. Mayo Clinic: Wrinkles: Treatments and Drugs: Soft Tissue Fillers

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