H1N1 vs. H5N1 WisdomCard

Our Guides and Physician Review team have organized the Top 10 Health Resources on H1N1 vs. H5N1 and compiled helpful research notes below.


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Research Notes on H1N1 vs. H5N1


H1N1, also referred to as swine flu, is a respiratory disease caused by influenza type A.1 H5N1, also known as avian influenza, is a highly contagious virus subtype among birds with infections that have occurred among humans who've had close contact with birds.2 The H1N1 type A influenza virus regularly causes outbreaks of influenza in pigs, while the H5N1 virus causes outbreaks in birds, and both can result in human-to-human transmission.3

Fast Facts:

  • H1N1 is a new virus strain that was first detected in the United States in April 2009.4
  • This H1N1 strain is a derivative of the H1N1 virus that caused the 1918 flu pandemic.5
  • As of May 2009, the Centers for Disease Control has reported an estimated 279 cases and 1 death from the H1N1 virus in the United States,6 with almost 1000 worldwide confirmed cases.7
  • The H5N1 virus infection of 2005 resulted in 122 cases of infections in humans and 62 deaths across thirteen countries in Asia and Europe.3
  • Influenza viruses keep changing. They mutate, and they exchange genetic material with other flu viruses.3
  • It has been demonstrated by the research literature that the H5N1 virus causes mutations in human genes which lead to a more pathogenic and severe form of the disease.8

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Research Notes References

  1. WHO: Influenza A(H1N1)
  2. CDC: Influenza Avian Influenza (Flu) - Key Facts About Avian Influenza
  3. 3.0 3.1 3.2 Avian Influenza News and Information: Avian Influenza Mutation, H5N1
  4. CDC: Questions and Answers About Novel H1N1 Flu (Swine Flu)
  5. New England Journal of Medicine: The Persistent Legacy of the 1918 Influenza Virus (July 16, 2009)
  6. CDC: H1N1 Flu (Swine Flu)
  7. CNN: Confirmed Cases of H1N1 Virus Approach 1,000 (May 4, 2009)
  8. Journal of General Virology: Differential Onset of Apoptosis in Influenza A Virus H5N1- and H1N1-infected Human Blood Macrophages (Oct. 10, 2007)

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  • Redirects: H1N1 vs H5N1, H5N1 vs H1N1, Swine flu vs avian flu, Avian flu vs swine flu, Comparing swine flu to avian flu, Comparing avian flu to swine flu, Comparing H1N1 to H5N1, Comparing H5N1 to H1N1
  • Last update: Sep. 28, 2009

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