Glucosamine Effectiveness WisdomCard


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Research Notes on Glucosamine Effectiveness


The effectiveness of the nutritional supplement, glucosamine has often been questioned and new research studies continue to challenge its validity.1 Glucosamine is a natural compound found in healthy joints, and many believe that glucosamine supplementation can help arthritis sufferers,2 however a proven treatment method has yet to be identified.3 As such, oral glucosamine supplementation has emerged as the treatment alternative for some patients.3

Fast Facts:

  • Glucosamine is thought to alleviate existing joint pain as well as helping to slow or prevent the degeneration of joint cartilage.3
  • In the first study to investigate glucosamine’s effectiveness for long-term pain control there was no significant difference between the percentage of participants who flared in the placebo group versus the glucosamine group.4
  • Despite the studies, some laboratory tests show that glucosamine may help protect joint cartilage by limiting breakdown and helping to build up levels of cartilage.3
  • When combined with other supplements, such as chondroitin, glucosamine has been proven to be effective.5


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Research Notes References

  1. About.com: Glucosamine Effectiveness Challenged
  2. Mayo Clinic: Glucosamine
  3. 3.0 3.1 3.2 3.3 Spine Health: Effectiveness of Glucosamine and Chondroitin Sulfate for Osteoarthritis
  4. About.com: Canadian Glucosamine Study: Glucosamine Shows No Long-Term Benefit
  5. Ayushveda: Taking Better Care of Your Joints

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Each WisdomCard is handcrafted by our team of physician-guided health advocates. Our goal is to make it easy for you to find the most useful health resources for any health topic by filtering out spam and bad links.