Effects of Ampicillin on Oral Contraceptives WisdomCard™

Our Guides and Physician Review team have organized the Top 10 Health Resources on Effects of Ampicillin on Oral Contraceptives and compiled helpful research notes below.

  1. MedicineNet: Ampicillin - Drug Interactions medicinenet.com - Ampicillin - Drug Interactions
  2. Drugs.com: Ampicillin drugs.com - Ampicillin
  3. PDRHealth: Special warnings about Ampicillin pdrhealth.com - Special warnings about Ampicillin
  4. AHFS Drug Information (via Healthline): Drug Interactions healthline.com - Drug Interactions
  5. RxList: Principen – Side Effects and Drug Interactions rxlist.com - Principen – Side Effects and Drug Interactions
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Research Notes on Effects of Ampicillin on Oral Contraceptives


Ampicillin may decrease the effectiveness of oral contraceptives when taken concurrently. Some medical experts suggest that other methods of contraception be used to prevent pregnancy while others claim that there is no need to. Ampicillin decreases the blood concentration of estrogen which makes the birth control pills less effective.

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