Depression and Chronic Fatigue WisdomCard

Our Guides and Physician Review team have organized the Top 10 Health Resources on Depression and Chronic Fatigue and compiled helpful research notes below.


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Research Notes on Depression and Chronic Fatigue


Chronic fatigue and depression often coexist. These two disorders are known to cause one another. Depression can lead to fatigue because of the sleeping problems associated with it. Fatigue can lead to depression because of the mental distress it causes. Chronic fatigue and depression are both treatable disorders.1

Fast Facts:

  • Even mild depression can cause fatigue.2
  • Studies show that depressed people are more than four times more likely to experience fatigue than those who are not depressed.3
  • People who experience fatigue are up to three times more likely to develop depression than those who are not.3
  • Though depression and fatigue are separate conditions with separate risk factors, many of their symptoms overlap.3

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Research Notes References

  1. Aphrodite Women's Health: Depression And Fatigue A Vicious Cycle
  2. Harvard Medical School: Depression And Anxiety - What Causes Fatigue: Chronic Fatigue
  3. 3.0 3.1 3.2 WebMD: Depression, Fatigue May Fuel Each Other

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