Depression Medication and Weight Gain WisdomCard™

Our Guides and Physician Review team have organized the Top 10 Health Resources on Depression Medication and Weight Gain and compiled helpful research notes below.

  1. Mayo Clinic: Antidepressants and Weight Gain: What Causes It? mayoclinic.com - Antidepressants and Weight Gain: What Causes It?
  2. MSN Health and Fitness: Antidepressants and Weight Gain Question health.msn.com - Antidepressants and Weight Gain Question
  3. WebMD: Up to 25% of People Who Take Antidepressants Gain Weight. Is There Anything You Can Do About It? webmd.com - Up to 25% of People Who Take Antidepressants Gain Weight. Is There Anything You Can Do About It?
  4. eMedTV: Antidepressants and Weight Gain depression.emedtv.com - Antidepressants and Weight Gain
  5. HealthyPlace: Weight Gain in a Pill healthyplace.com - Weight Gain in a Pill
  6. Your Total Health: Antidepressants & Weight Gain yourtotalhealth.ivillage.com - Antidepressants & Weight Gain
  7. Cleveland Clinic Journal of Medicine: Managing Weight Gain as a Side Effect of Antidepressant Therapy ccjm.org - Managing Weight Gain as a Side Effect of Antidepressant Therapy
  8. Berkeley Parents Network: Weight Gain on Antidepressants parents.berkeley.edu - Weight Gain on Antidepressants
  9. About.com: Weight Matters depression.about.com - Weight Matters
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Research Notes on Depression Medication and Weight Gain


Weight gain is a genuine concern for patients beginning or already taking a medication for depression. Many people gain weight while taking antidepressants.1 This is a primary reason that patients do not comply with treatment protocols. Poor treatment outcomes are often the result.2

Fast Facts:

  • It is not clear why weight gain occurs with antidepressants.3
  • Higher doses are often responsible for more weight gain.4
  • If you're on a specific antidepressant and you're in remission, ask your doctor about decreasing the dose.4

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Research Notes References

  1. ↑ eMedTV:Antidepressants and Weight Gain
  2. ↑ Cleveland Clinic Journal of Medicine: Managing Weight Gain as a Side Effect of Antidepressant Therapy
  3. ↑ eMedTV: Antidepressants and Weight Gain
  4. ↑ 4.0 4.1 Your Total Health: Antidepressants & Weight Gain

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