Darunavir WisdomCard


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Research Notes on Darunavir


Darunavir (Prezista) is a drug used to treat HIV infection. It is in the protease inhibitor class. Developed by pharmaceutical company Tibotec, darunavir is named after Arun K. Ghosh, the chemist who discovered the molecule at the University of Illinois in Chicago. It was approved by the Food and Drug Administration (FDA) on June 23, 2006. Darunavir is a second-generation protease inhibitor (PIs), designed specifically to overcome problems with the older agents in this class, such as indinavir. Early PIs often have severe side effects and drug toxicities, require a high therapeutic dose, are costly to manufacture, and show a disturbing susceptibility to drug resistant mutations. Such mutations can develop in as little as a year of use, and effectively render the drugs useless....read more at Wikipedia

Fast Facts:

  • Darunavir does not reduce the risk of passing HIV to others.1
  • When used with other anti-HIV medications, darunavir may reduce the amount of HIV in your blood and increase your CD4 cell count.1
  • Darunavir is usually taken twice daily with ritonavir.2


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Research Notes References

  1. 1.0 1.1 U.S. Food and Drug Administration: Darunavir Patient Information
  2. The American Society for Health-System Pharmacists (via MedlinePlus): Darunavir

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