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Chiari I Malformation


Research Notes on Chiari I Malformation


Chiari malformation type I is a congenital defect that leads to structural defects in the cerebellum. The abnormality leads to a downward push of the cerebellar tonsils and other brain tissue into the spinal canal. This can lead to a blockage of the cerebral spinal fluid outflow. Headaches, muscle soreness, and low energy levels can result. Chiari-I malformations are diagnosed by a physical exam, x-ray’s, CT scan, and/or MRI.1 Genetic counseling is recommended to provide information on the recurrence risks and genetic testing availability.2

Fast Facts:

  • The prevalence of this condition is around 1 in 1,000 live births.3
  • Defects of the cerebellum occurs during fetal development and can affect the coordination of movement during childhood.4
  • Abnormalities of the cerebellum appear in 30-50 percent of patients with Chiari I malformation.3

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Research Notes References

  1. MayField Clinic: Chiari-1 Malformation
  2. New York University Langone Medical Center: Prevention
  3. 3.0 3.1 University of Southern Clalifornia Neurological Surgery: Type I Chiari Malformation
  4. Neurosurgery Today: Chiari-1 Malformation

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