Bipolar Medications and Pregnancy WisdomCard

Our Guides and Physician Review team have organized the Top 10 Health Resources on Bipolar Medications and Pregnancy and compiled helpful research notes below.


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Research Notes on Bipolar Medications and Pregnancy


Careful planning is important for women with bipolar disorder who want to become pregnant. Many bipolar medications have been shown to be harmful to the fetus, but discontinuing medication is also highly dangerous for the mother. Symptoms of bipolar disorder usually increase during pregnancy and after delivery. Planning, well before conception, can help reduce the risks to both baby and mom.1

Fast Facts:

  • Studies show that there is less risk to the developing fetus when only one mood stabilizer is used during pregnancy.1
  • Depakote is a bipolar medication that has been proven to cause harm to the fetus and is typically not recommended during pregnancy.1
  • Discontinuing treatment of bipolar disorder during pregnancy greatly increases the risk of depressive episodes.2
  • You can learn about other treatment options for bipolar disorder from our psychiatrists!

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Research Notes References

  1. 1.0 1.1 1.2 National Alliance on Mental Illness: Managing Pregnancy and Bipolar Disorder
  2. Massachusetts General Hospital Bipolar Disorder and Pregnancy: Should Medications Be Discontinued?

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