Benign Focal Epilepsy WisdomCard

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Research Notes on Benign Focal Epilepsy


Benign familial neonatal convulsions (BFNC) is a rare autosomal dominant inherited form of epilepsy. It manifests in newborns, normally within the first 7 days of life, as tonic-clonic seizures. Infants are otherwise normal between attacks and develop without incident. Attacks normally spontaneously cease within the first 15 weeks of life. Lifetime susceptibility to seizures is increased, as 16% of those diagnosed with BFNC earlier in life will go on to have seizures versus a 2% lifetime risk for the general population. There are three known genetic causes of BFNC, two being the voltage-gated potassium channels KCNQ2 (BFNC1) and KCNQ3 (BFNC2) and the third being a chromosomal inversion (BFNC3). There is no obvious correlation between most of the known mutations and clinical variability seen in BFNC. ...more from Wikipedia

Fast Facts:

  • Also called idiopathic partial epilepsy.1
  • Typically easy to control and usually disappears by age 16 with or without treatment. 2
  • Cannot be attributed to a known underlying condition.3

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Research Notes References

  1. Cleveland Clinic (via WebMD): Types of Epilepsy: Idiopathic Partial Epilepsies
  2. Epilepsy Foundation: Benign Focal Epilepsy of Childhood
  3. New York University Medical Center: Idiopathic Partial Epilepsy

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