Angiogenesis Inhibitors WisdomCard™
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Research Notes on Angiogenesis Inhibitors
An angiogenesis inhibitor is a substance that inhibits angiogenesis (the growth of new blood vessels). It can be endogenous or come from outside as drug or a dietary component. Every solid tumor (in contrast to liquid tumors like leukemia) needs to generate blood vessels to keep it alive once it reaches a certain size. Usually, blood vessels are not built elsewhere in an adult body unless tissue repair is actively in process. The angiostatic agent endostatin and related chemicals can suppress the building of blood vessels, preventing the cancer from growing indefinitely. In tests with patients, the tumor became inactive and stayed that way even after the endostatin treatment was finished. The treatment has very few side effects but appears to have very limited selectivity. Other angiostatic agents like thalidomide and natural plant-based substances are being actively investigated. ...read more at Wikipedia
Fast Facts
- Scientists are currently researching ways to use angiogenesis inhibitors to prevent cancer growth in humans.1
- Angiogenesis inhibitors are being used in clinical trial studies for treatment in for lung cancer, breast cancer, renal cell carcinoma, metastatic colorectal cancer, high grade gliomas, and other types of cancers. 2
- Dr. Judah Folkman, a pediatric surgeon at the Children’s Hospital Boston, pioneered the concept of cancer anti-angiogenic therapy in the 1970's 3
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Latest Headlines on Angiogenesis Inhibitors
What is Angiogenesis Inhibitors?
- UAB Health System: What are Angiogenesis Inhibitors?
- Angio.org: Understanding Angiogenesis
- MD Foundation: Thalidomide and Other Angiogenesis Inhibitors
What Are The Uses for Angiogenesis Inhibitors?
- Mayo Clinic: Angiogenesis Inhibitors: New Cancer Drugs Stop Tumor Growth
- ScienceDaily: FDA Approves First Angiogenesis Inhibitor To Treat Colorectal Cancer
What Are The Side Effects, Interactions and Precautions for Angiogenesis Inhibitors?
- National Cancer Institiute: Angiogenesis Inhibitors Therapy: Does Angiogenesis Inhibitor Therapy Have any Complications or Side Effects?
- eHow: Understand the Side Effects of Angiogenesis Inhibitors
What are the Alternatives to Angiogenesis Inhibitors?
- OrganizedWisdom: Chemotherapy
- OrganizedWisdom: Radiation Therapy
- American Cancer Society: Photodynamic Therapy
- Cancer Research UK: Different Types of Surgery for Lung Cancer
What are the Holistic Alternatives to Angiogenesis Inhibitors?
- The Cancer Cure Foundation: What is Alternative Therapy?
- University of California, San Diego Medical Center: Moores Cancer Center: Complementary and Alternative Therapies For Cancer Patients
Wisdom, Blogs, and Message Boards about Angiogenesis Inhibitors
- MedHelp: Discussion on Angiogenesis Inhibitors
- HealthBoards: Enzastaurin - Anyone ?
- ScienceDaily: New Oral Angiogenesis Inhibitor Offers Potential Nontoxic Therapy For A Wide Range Of Cancers (Jun 30, 2008)
Clinical Trials for Angiogenesis Inhibitors
- ClinicalTrials.gov: Angiogenesis Inhibitors Clinical Trial Listings
- CenterWatch: Angiogenesis Inhibitors Clinical Trials
Controversy and Lawsuits about Angiogenesis Inhibitors
- ScienceDaily: Blocking Angiogenesis Signaling From Inside Cell May Lead To Serious Health Problems, Study Finds (Aug 24, 2007)
Scientific and Medical Journal Articles on Angiogenesis Inhibitors
- PubMed Central: Angiogenesis Inhibitors Articles
- JAMA: Archives of Angiogenesis Research
- Google Scholar: Articles on Angiogenesis Inhibitors
Research Notes References
- ↑ UAB Health System: What are Angiogenesis Inhibitors?
- ↑ UptoDate: Overview of Angiogenesis Inhibitors
- ↑ The Childhood Brain Tumor Foundation: Angiogenesis Inhibitors – A New Frontier in Cancer Therapy
About this WisdomCard
- Contributor: Tara Salamone
- Reviewer: Nicole Kinsey
- Supervised by: The OrganizedWisdom Physician Review Team
- Last update: Oct. 14, 2009
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About WisdomCard
Meet our contributors and reviewers
- Contributor: Tara Salamone
- Reviewer: Nicole Kinsey
- Supervised by: The OrganizedWisdom Physician Review Team
- Redirects: Angiogenesis Inhibitor, Angiostatic agent, Angiostatic agents
- Last update: Jul. 3, 2008
Each WisdomCard is handcrafted by our team of physician-guided health advocates. Our goal is to make it easy for you to find the most useful health resources for any health topic by filtering out spam and bad links.
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