A-a Oxygen Gradient WisdomCard™

Our Guides and Physician Review team have organized the Top 10 Health Resources on A-a Oxygen Gradient and compiled helpful research notes below.

  1. ValueMD: A-a Gradient valuemd.com - A-a Gradient
  2. Mad Scientist Software Inc: Blood Gases madsci.com - Blood Gases
  3. Journal Watch: A-a Gradient Is Of Little Use In Evaluating For PE emergency-medicine.jwatch.org - A-a Gradient Is Of Little Use In Evaluating For PE
  4. Chest Journal: Alveolar-Arterial Oxygen Gradient In The Assessment Of Acute Pulmonary Embolism chestjournal.org - Alveolar-Arterial Oxygen Gradient In The Assessment Of Acute Pulmonary Embolism
  5. Med Calc 3000: A-a Gradient medcalc3000.com - A-a Gradient
  6. LabPlus: Alveolar - Arterial Oxygen Gradient adhb.govt.nz - Alveolar - Arterial Oxygen Gradient
  7. Medscape: The A-a Gradient medscape.com - The A-a Gradient
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Research Notes on A-a Oxygen Gradient


The A-a oxygen gradient is a measure of how effectively oxygen is being transferred from the lungs to the blood.1 In a healthy lung, when inhaling would match exhaling exactly, there would be no difference between these two and the gradient would be zero.2 The gradient is most effective when the patient has been breathing “ambient air” for at least five minutes.1

Fast Facts:

  • A mismatch of the V/Q levels is the most common cause of hypoxemia.2
  • The hypoxemia caused from this can be corrected by giving 100% oxygen.2
  • If the PaO2 level remains low with the use of oxygen, a shunt can be used.2

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Research Notes References

  1. ↑ 1.0 1.1 LabPlus: Alveolar - Arterial Oxygen Gradient
  2. ↑ 2.0 2.1 2.2 2.3 Medscape: The A-a Gradient

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